GLP-3
RTBatch: PRV-RT30Q-060926P
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For Research & Laboratory Use Only
This product is intended solely for in vitro research. Not for human or veterinary use.
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99%+ Identity Purity
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Batch PRV-RT30Q-060926P
About GLP-3
Triple GLP-1/GIP/Glucagon Receptor Agonist GLP-3 (RT), also known or LY3437943, is a synthetic 39-amino-acid peptide investigated for its activity at three metabolic receptors: the glucagon-like peptide-1 receptor (GLP-1R), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon receptor (GCGR). Its triple-receptor activity has made GLP-3 (RT) an important compound in research examining incretin signalling, receptor activation, glucose-insulin pathways, energy regulation and cellular nutrient metabolism. GLP-3 (RT) incorporates amino-acid substitutions designed to support receptor activity and resistance to enzymatic degradation. It also contains a C20 fatty diacid modification that promotes albumin binding and extends its exposure profile in experimental models. Areas of Research: Published research has examined GLP-3 (RT) in relation to: GLP-1, GIP and glucagon receptor activation Multi-receptor signalling pathways Glucose-dependent insulin signalling Cellular nutrient and lipid metabolism Energy expenditure and energy-balance mechanisms Receptor binding and downstream signalling Metabolic regulation in experimental models
